Exim4 config help request

[Ishwar Rattan <ishwar@pali.cps.cmich.edu>]

I just installed ProMepis and it installs by default exim4
SMTP service. I am looking for a simple working configuration for
exim4 (I have been using Sendmail and have tried Postfix too!).

Requirements is that it should send to and receive from remote
domains (office box connected to Internet via LAN). The error
message sent back by exim is:

  ...
  Mailing to remote domains is not supported

in fact, it does not send to another machine in the same domain!

Any pointers will be appreciated.

-ishwar