Hi Michael, and people at ease with architecture ports,
The package brian has a mechanism based on the GSL which does
some sort of compilation just-in-time. The default set of build
flags works rather well on all flavors of amd64 architecture
with or without extensions, however not all of the specified
options by default are supported on all architectures.
Hmm.. this sounds like a recipe for a tough time :-D
Personally I put no extra effort for mips :-)
-march=native is not allowed as it violates the architecture baseline, unless there is an alternative binary or library built without it.