Re: Is Churchill revolutionary?

[Scott Christley <schristley@me.com>]

On Feb 11, 2015, at 9:32 AM, Roland Fehrenbacher <rf@q-leap.de> wrote:

> 
> Anyone can judge the real impact of this?
> 

Other groups have worked on similar capability.

http://bioinformatics.oxfordjournals.org/content/early/2014/02/12/bioinformatics.btu071.abstract

These are essentially data-parallel solutions. What I’ve found is that most of these workflows utilizing existing software, e.g. BWA for alignment and GATK for variant calling, but they take different approaches to splitting the large data set, running the tools on that data in parallel, and then merging the results.  Churchill does look to be pretty fast though.

cheers
Scott