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Bug#643324: ITP: profphd -- secondary structure and solvent accessibility predictor



On Tue, Sep 27, 2011 at 11:24:44AM +0200, Laszlo Kajan wrote:
> Package: wnpp
> Severity: wishlist
> Owner: Laszlo Kajan <lkajan@rostlab.org>
> 
> 
> * Package name    : profphd
>   Version         : 1.0.35
>   Upstream Author : Laszlo Kajan <lkajan@rostlab.org>
> * URL             : http://rostlab.org/
> * License         : GPL
>   Programming Lang: Perl
>   Description     : secondary structure and solvent accessibility predictor
> 
> Solvent accessibility is predicted by a neural network method rating at a
> correlation coefficient (correlation between experimentally observed and
> predicted relative solvent accessibility) of 0.54 cross-validated on a set of
> 238 globular proteins (Rost & Sander, Proteins, 1994, 20, 216-226;
> evaluation of accuracy). The output of the neural network codes for 10 states
> of relative accessibility. Expressed in units of the difference between
> prediction by homology modelling (best method) and prediction at random
> (worst method), PROFacc is some 26 percentage points superior to a comparable
> neural network using three output states (buried, intermediate, exposed) and
> using no information from multiple alignments.

These paragraphs sound like a scientific abstract or part of a
scientific paper.  The long description is supposed to help me (as a
sysadmin) decide whether or not I want to install the package.  Perhaps
you could simply describe what the package itself is good for and
include the minimum background necessary for me to understand so I can
make a decision.

-- 
brian m. carlson / brian with sandals: Houston, Texas, US
+1 832 623 2791 | http://www.crustytoothpaste.net/~bmc | My opinion only
OpenPGP: RSA v4 4096b: 88AC E9B2 9196 305B A994 7552 F1BA 225C 0223 B187

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