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Bug#623731: RFP: ugene -- integrated bioinformatics tools



Package: wnpp
Severity: wishlist

* Package name    : ugene
* URL             : http://ugene.unipro.ru/
* License         : GPL
  Description     : integrated bioinformatics tools

Unipro UGENE: Integrated Bioinformatics Tools
 UGENE is a free cross-platform genome analysis suite. 
 It works perfectly on Windows, Mac OS or Linux and requires only a few clicks to install. 
   Features 

   Screenshots 

 Feature-rich sequence viewer and annotator 
 Swine flu in UGENE 


 Workflow Designer visual interface 
 Workflow Designer 


 Multiple sequence alignment editor 
 Multiple alignment 
  Integrated tools 
 Multiple sequence alignment using MUSCLE 3, KAlign, Clustal; 
 HMM profiles build and search, based on the source of HMMER 2 and HMMER 3; 
 PCR Primers design using Primer 3; 
 Cloning in silico capabilities; 
 Queries to NCBI BLAST and CDD databases; 
 Protein secondary structure prediction using GOR IV and PSIPRED; 
 Phylogenetic analysis with Phylip; 
 Search for restriction enzymes and integration with REBASE; 
 Extremely fast repeat finder; 
 DNA reference assembly using Bowtie; 
 Search for transcription factor binding sites using SITECON; 
 Protein back translation; 
 ORF finder; 
 Complete Smith-Waterman algorithm implementation; 
 Support for external tools: BLAST+, MAFFT, T-Coffee. 

   User interface 
 Visual and interactive genome browsing including circular plasmid view; 
 Multiple alignment editor; 
 Chromatograms visualization; 
 3D viewer for files in PDB and MMDB formats with anaglyph stereo mode support; 
 Phylogenetic tree viewer; 
 Dot plot visualization; 
 Query designer enables search for complex annotation patterns; 
 Easy to use workflow designer for custom computational workflows. 

   High performance computing in UGENE 
 Complete support of modern multicore processors and SSE instructions; 
 Out of the box support of modern GPUs using NVIDIA CUDA and ATI Stream; 
 Support for cloud computing: running computational tasks on Amazon EC2 cloud; 
 Support for supercomputers and distributed computing. 

   Cooperation  
 Can be used for education purposes in schools and universities; 
 Features to be included into the next release are initiated by users; 
 UGENE team is ready for collaboration in related projects, both free or commercial. 



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