Bug#530007: ITP: r-other-mott-happy -- GNU R package for fine-mapping complex diseases

[Steffen Moeller <steffen_moeller@gmx.de>]

Package: wnpp
Severity: wishlist
Owner: Steffen Moeller <steffen_moeller@gmx.de>

* Package name    : r-other-mott-happy
  Version         : 2.1
  Upstream Author : Richard Mott <Richard.Mott@well.ox.ac.uk>
* URL             : http://www.well.ox.ac.uk/happy/happyR.shtml.
* License         : GPL-2+
  Programming Lang: C,R
  Description     : GNU R package for fine-mapping complex diseases

 The idea behind this package is that when multiple strains of
 animals that differ in their susceptibility to multiple diseases
 are bread over multiple generations, then one can analyse the
 contribution that a particular genetic locus has to each of those
 diseases. While in the past this approach has been performed
 for one disease at a time, this tool extends the statistics
 for allowing multiple crosses and thus save animal lifes. A larger
 stock of animals with more generations to keep them will further
 help producing larger numbers of observable cross-over events
 and thus help increasing the resolution of the mapping.
 .
 happy is an R interface into the HAPPY C package for fine-mapping
 Quantitative Trait Loci (QTL) in Heterogenous Stocks (HS). An HS is
 an advanced intercross between (usually eight) founder inbred strains
 of mice. HS are suitable for fine-mapping QTL. The happy package is
 an extension of the original C program happy; it uses the C code to
 compute the probability of descent from each of the founders, at each
 locus position, but the happy packager allows a much richer range of
 models to be fit to the data.