On December 20, 2017 5:17:20 AM EST, Michael Crusoe <michael.crusoe@gmail.com> wrote:
2017-12-16 10:18 GMT+02:00 Afif Elghraoui <afif@debian.org>:
Hi, all,
Given the statement from the website [1]
Please note that TopHat has entered a low maintenance, low support
stage as it is now largely superseded by HISAT2 which provides the
same core functionality (i.e. spliced alignment of RNA-Seq reads),
in a more accurate and much more efficient way
This statement is about TopHat 2, which is what is in the Debian
package
tophat
and a statement from one of its co-authors [2]
Please stop using Tophat. Cole and I developed the
method in *2008*. It was greatly improved in TopHat2 then HISAT
& HISAT2. There is no reason to use it anymore. I have been
saying this for years yet it has more citations this year than last
This more strongly worded statement is about TopHat 1, which is not in
Debian.
The summary of the statement is that hisat2 is the only one of those 4 that isn't obsolete, and therefore that it's the only one of those 4 that should be used.
We should retain TopHat2, perhaps with a note about HISAT2.
I think tophat2 (and hisat1 if we have it) should also be removed. We should get upstream involved if you still disagree.