After some discussion, it seems that libc6-i386 is the correct package for this bug. Reassigned. libc maintainers, please add a file to /etc/ld.so.conf.d/ in the libc6-i386 package containing the appropriate 32-bit multiarch path, "/usr/lib/i486-linux-gnu" or so, so that my shiny new multiarch-enabled Wine packages will actually run for amd64 users. Thanks.