[Date Prev][Date Next] [Thread Prev][Thread Next] [Date Index] [Thread Index]

Bug#797676: ITP: python-kineticstools -- detecting DNA modifications from single molecule, real-time sequencing data



Package: wnpp
Severity: wishlist
Owner: Debian Med Packaging Team <debian-med-packaging@lists.alioth.debian.org>
Control: block 787977 by -1

* Package name    : python-kineticstools
  Version         : 0.5.1
  Upstream Author : Pacific Biosciences <devnet@pacificbiosciences.com>
* URL             : https://github.com/PacificBiosciences/kineticsTools
* License         : BSD
  Programming Lang: Python
  Description     : detecting DNA modifications from single molecule, real-time sequencing data

kineticsTool loads IPDs observed at each position in the genome, and compares
those IPDs to value expected for unmodified DNA, and outputs the result of
this statistical test. The expected IPD value for unmodified DNA can come
from either an in-silico control or an amplified control. The in silico control
is trained by PacBio and shipped with the package. It predicts predicts the
IPD using the local sequence context around the current position. An amplified
control dataset is generated by sequencing unmodified DNA with the same
sequence as the test sample. An amplified control sample is usually generated
by whole-genome amplification of the original sample.

This package is part of the SMRT Analysis suite and is to be handled by the
Debian Med team.


Reply to: