Bug#680140: ITP: profbval -- PROFbval is a method for predicting residue mobility based on amino-acid sequence.

[to_anger@freenet.de]

Package: wnpp
Severity: wishlist
Owner: root <to_anger@freenet.de>


* Package name    : profbval
  Version         : 1.0.16
  Upstream Author : Guy Yachdav <gyachdav@rostlab.org> 
* URL             : http://www.predictprotein.org/docs.php
* License         : GPL
  Programming Lang: Perl
  Description     : predicts flexibile/rigid residues from sequence

  PROFbval is a neural-network based trained on backbone B-value data from X-ray structure. PROFbval was trained on a sequence
  unique set of high-resolution protein structures from the PDB.

  The mobility of a given residue on the protein surface is related to its functional role. A common measure of atom mobility in
  proteins is B-value data from x-ray crystallography structures. PROFbval is a method predicting backbone B-values from amino-
  acid sequence. PROFbval can be useful for both protein structure and function predictions. For instance, a biologist can
  locate potentially antigenic determinants by identifying the most flexible residues on the protein surface. Additionally, a
  crystallographer can locate residues that potentially have high experimental B-values.