I do not know exactly Palp, but I can tell you that if you try to run a program that was written for sequential machines, on a multicore machine, most likely you will not get any benefit.. The solution is to rewrite program for example to use quad-core CPUs.
If you're thinking of running a program on beowulf architectures, in this case too the solution is to rewrite the program in a way that it can run in parallel on the nodes of beowulf cluster.
Data: 21/06/2011 20.05
Ogg: Beowulf in BioinformaticsHello all, my name is Guilherme Rocha, Biotechnologist and a Debian user since Potato, a stupid older user that think to be an advanced user, no more than this. Help sometimes to Debian l10n team to localize Debian to PT_BR. I'm in charge to plan and build a cluster in our lab. Our lab is Genev - Laboratory of Genetics of Population and Molecular Evolution, in the Federal University of Bahia - Brasil. We already have some tasks being done in a Ubuntu Dell Server Machine, but in a very slow procedure. In a Dell quadcore running Ubuntu this task (PALP analysis) delay 9 days to be done. We want to reduce this time drastically. So we want to listen you, gurus, about the best practices in order to do it, and also, to understand if we will have a significant time reduction with our hardware, described below.
- We first need to identify what we want/need. what is the (typical) problem you want to solve?To use Debian Med in order to make philogenetics analysis, protein modeling, DNA alignment, genetics stuff... Open Softwares like PALP, GAMGI, GARLIC, GDPC, PyMOL, Perl Primer, etc...
- what software do you need for that, do you need a batch scheduler or do you
have very few users which work at the same place and share the cluster without technical measures?We'll have very few people, 10 I think. Not sure if the tasks need to be scheduled to be run. We are intended to use Debian Med, (med-bio meta-package) running in a small size beowulf cluster. Almost 10 to 15 nodes.
- think about the OS (Debian is a good choice here ;))Yes, sure, Debian Med. :)
- Think about the compute hardware, you probably need a login node, execute nodes and a file server, do you need many local cores or are the problems too large to fit into a few nodes?We have very obsolete hardware, our server-node will be a pentium IV 1,5GHz with 1GB RAM, with work-nodes from k6-500MHz (5 unities) to pentium III 266MHz (10 unities), Thin Clients ATOM 1GHz Question: ThinClients with ATOM processor could be used? The performance will be good enough? Then you need to look into networking (Infiniband or high performance Ethernet), is the software susceptible to latency and/or bandwidth available...... We have a 10/100 Switch. We are looking to the possibility to acquire a 100/100/1000 switch. So the questions are:
- With this hardware, we will have a significant time reduction on these tasks with our hardware?
- Can we use thin clients to build a cluster?
- Some "Debian beowulf Way" method to be reviewed before start?
- Another type of cluster may be better than Beowulf to do it?
- Any Idea will be very welcomecheers and long life to Debian,-- Guilherme Rocha GF7 Doc & Systems - Soluções Tecnológicas Home Page: http://www.gf7.com.br Telefone: + 55 71 4062 9142 Mobile: + 55 71 9279 0829