MySQL breaks after upgrading (Sid)

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After upgrading last night, I realized that MySQL server has stop.
After checking what's going on from /var/log/syslog, I decided to
uncomment line max_allowed_packet=16M on my.cf
Then restart mysql server and it run well.
Wonder if anyone experienced this.

---me---

syslog:

Sep 30 19:15:25 mslinuz mysqld_safe[27711]:
Sep 30 19:15:26 mslinuz mysqld_safe[27779]: started
Sep 30 19:15:26 mslinuz mysqld[27782]: /usr/sbin/mysqld: ready for 
connections.
Sep 30 19:15:26 mslinuz mysqld[27782]: Version: '4.0.21-log'  socket: 
'/var/run/mysqld/mysqld.sock'  port: 3306  Source distribution
Sep 30 19:15:32 mslinuz /etc/init.d/mysql[27827]: 4 processes alive and 
'/usr/bin/mysqladmin --defaults-extra-file=/etc/mysql/debian.cnf ping' 
resulted in
Sep 30 19:15:32 mslinuz /etc/init.d/mysql[27827]: /usr/bin/mysqladmin: 
unknown variable 'max_allowed_packet=16M'
Sep 30 19:15:32 mslinuz /etc/init.d/mysql[27827]:

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