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To study single molecules, Block has pioneered the use of optical tweezers, tiny laser-based "tractor beams" that produce miniscule piconewton forces to drag around molecules and allow measurements of displacements on the order of a nanometer. "You can stop and stall molecules, w follow their motion. Recently, we've studied the backtracking of RNA polymerase: when it makes a mistake, it can actually back up by five bases, scoop off the wrong thing and start again," says Block. While biological nanotechnology "hasn't even arrived at its infancy yet," says Block, "biological nanoscience is a very exciting place to be right now, because the techniques now exist to truly study proteins, and we're learning so much about them."








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"Whether nanotechnology had ever showed up or not, electronics would have gotten there anyway," says Professor Saraswat. For the past four decades, the number of transistors that can be put on a chip, or equivalently, the number of information processing events that can be done per chip, has doubled every twenty-two months; concomitantly, the cost per processing event has dropped. Following this trend called Moore's Law, microelectronics has steadily settled into nanoelectronics in the past decade.
In your brain right now, a motor protein called kinesin is shuttling vesicles loaded with neurotransmitters to the synapses in your brain, allowing you to read this. While some researchers are trying to make similar molecular motors scoot around and throw switches on electronic chips, it's hardly certain these motors can ever do better than the electrical contacts that are routinely used today. The future of biological nanotechnology may not be clear, but what is, says Professor



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